SMILE

Stochastic Models for the Inference of Life Evolution

Bibtex

@article{segura_evolution_2013,
Author = {Segura, Joana and Ferretti, Luca and Ramos-Onsins,
Sebastián and Capilla, Laia and Farré, Marta and
Reis, Fernanda and Oliver-Bonet, Maria and
Fernández-Bellón, Hugo and Garcia, Francisca and
Garcia-Caldés, Montserrat and Robinson, Terence J. and
Ruiz-Herrera, Aurora},
Title = {Evolution of recombination in eutherian mammals:
{Insights} into mechanisms that affect recombination
rates and crossover interference},
Journal = {Proceedings. Biological Sciences / The Royal Society},
Volume = {280},
Number = {1771},
Pages = {20131945},
abstract = {Recombination allows faithful chromosomal segregation
during meiosis and contributes to the production of new
heritable allelic variants that are essential for the
maintenance of genetic diversity. Therefore, an
appreciation of how this variation is created and
maintained is of critical importance to our
understanding of biodiversity and evolutionary change.
Here, we analysed the recombination features from
species representing the major eutherian taxonomic
groups Afrotheria, Rodentia, Primates and Carnivora to
better understand the dynamics of mammalian
recombination. Our results suggest a phylogenetic
component in recombination rates (RRs), which appears
to be directional, strongly punctuated and subject to
selection. Species that diversified earlier in the
evolutionary tree have lower RRs than those from more
derived phylogenetic branches. Furthermore,
chromosome-specific recombination maps in distantly
related taxa show that crossover interference is
especially weak in the species with highest RRs
detected thus far, the tiger. This is the first example
of a mammalian species exhibiting such low levels of
crossover interference, highlighting the uniqueness of
this species and its relevance for the study of the
mechanisms controlling crossover formation,
distribution and resolution.},
doi = {10.1098/rspb.2013.1945},
issn = {1471-2954},
language = {eng},
month = nov,
pmcid = {PMC3790489},
pmid = {24068360},
shorttitle = {Evolution of recombination in eutherian mammals},
year = 2013
}